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Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay

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Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay

China Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay supplier
Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay supplier Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay supplier

Large Image :  Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay

Product Details:

Place of Origin: China
Model Number: 62-44-2

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: USD 60/kg
Packaging Details: 1kg/bag; 25kg/drum
Delivery Time: 1-3days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 10000kg/month
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Detailed Product Description
Synonym: Acetophenetidin; 4-acetophenetidine CAS: 62-44-2
Purity: 99%

Quick details:

 

Product Name: Phenacetin
Synonyms: 1-ACETYL-P-PHENETIDIN;4-ACETOPHENETIDIDE;4-acetophenetidine;4'-ETHOXYACETANILIDE;4-ETHOXYACETANILIDE;ACETOPHENETIDIN;ACETOPHENETIDINE;ACET-P-PHENETIDINE
CAS: 62-44-2
MF: C10H13NO2
MW: 179.22
EINECS: 200-533-0
Assay: 99%
Packing: 25kg/drum
Appearance: White powder

 

Melting point 133-136 °C(lit.)
Boiling point 132 °C / 4mmHg
density 1.1248 (rough estimate)
refractive index 1.5710
Fp 2℃
storage temp. 2-8°C
form powder
color White
Water Solubility 0.076 g/100 mL
Sensitive Hygroscopic
Merck 14,7204
BRN 1869238
Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
InChIKey CPJSUEIXXCENMM-UHFFFAOYSA-N

 

Phenacetin (or acetophenetidin) is a pain-relieving and fever-reducing drug.

Phenacetin was introduced in 1887 in Elberfeld, and was used principally as an analgesic; it was one of the first synthetic fever reducers to go on the market. It is also known historically to be one of the first non-opioid analgesics without anti-inflammatory properties.

 

Its analgesic effects are due to its actions on the sensory tracts of the spinal cord. In addition, phenacetin has a depressant action on the heart, where it acts as a negative inotrope. It is an antipyretic, acting on the brain to decrease the temperature set point. It is also used to treat rheumatoid arthritis (subacute type) and intercostal neuralgia.

It is metabolized in the body to paracetamol (acetaminophen), which is also a clinically relevant analgesic.

 

Phenacetin was widely used as a remedy for fever and pain. Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs. Due to its low cost, phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.

 

Since their synthesis in the late 1800s paracetamol (acetaminophen) and phenacetin have followed divergent pathways with regard to their popularity as mild analgesic/antipyretic drugs. Initially, paracetamol was discarded in favour of phenacetin because the latter drug was supposedly less toxic. Today the opposite is true, and paracetamol, along with aspirin, has become one of the two most popular ‘over-the-counter’ non-narcotic analgesic agents. This marked increase in the wide approval attained by paracetamol has been accompanied by the virtual commercial demise of phenacetin because of its role, albeit somewhat circumstantial, in causing analgesic nephropathy.

Both paracetamol and phenacetin are effective mild analgesics, suitable for treating mild to moderate pain, and their actions are broadly comparable with those of aspirin and related salicylates, although they do not appear to possess significant anti-inflammatory activity. Since a major portion of a dose of phenacetin is rapidly metabolised to paracetamol, it seems possible that phenacetin owes some of its therapeutic activity to its main metabolite, paracetamol, whereas its most troublesome side effect (methaemoglobinaemia) is due to another metabolite, p-phenetidine. The mechanism of action of paracetamol is poorly defined, although it has been speculated that it may selectively inhibit prostaglandin production in the central nervous system, which would account for its analgesic/antipyretic properties. The lack of any significant influence on peripheral cyclo-oxygenase would explain the absence of anti-inflammatory activity.

 

Terms of payment: T/T, WU, MG, BITCOIN
Delivery time: Within 1-3 days after your payment
Shipping method: Discreet package for shipping

Pharmaceutical Grade Phenacetin Powder CAS 62-44-2 Fever Reducing 99% Assay

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